Three key buildings of the sprawling area, comprised of thousands of stalls selling microchips, telephone parts, and other components to manufacturers, will stay closed until Sept 2.
Local community officials confirmed Monday's closure to Reuters, while three people working there said building managers had told them to work from home.
The same official Shenzhen channels called a halt to subway services at 24 stations in the central districts of Futian and Luohu.
On Monday, the tech hub of 18 million people reported nine symptomatic and two asymptomatic cases from testing the previous day.
(Reporting by David Kirton; Editing by Hugh Lawson and Clarence Fernandez)
People walk in front of the large screen showing the latest stock exchange data, in Shanghai, China, 22 August 2022. (Photo: EPA-EFE/ALEX PLAVEVSKI)