---
title: "Omicron sub-variants likely cause of SA's Covid-19 fifth wave: Here's all the latest information"
description: "Coronavirus infections continue to increase in South Africa, with Gauteng still accounting for most of the new infections in the country, followed by KwaZulu-Natal."
type: "NewsArticle"
publisher: "Daily Maverick"
site: "https://www.dailymaverick.co.za"
section: "COVID-19"
author: "Daily Maverick"
author_url: "https://www.dailymaverick.co.za/author/dailymaverick/"
canonical_url: "https://www.dailymaverick.co.za/article/2022-04-29-covid-19-fifth-wave-omicrone-sub-variants-south-africa/"
published: "2022-04-29T11:34:50"
updated: "2022-05-02T10:37:38"
lang: "en-ZA"
word_count: 124
---

# Omicron sub-variants likely cause of SA's Covid-19 fifth wave: Here's all the latest information

> Coronavirus infections continue to increase in South Africa, with Gauteng still accounting for most of the new infections in the country, followed by KwaZulu-Natal.

By Daily Maverick · Published 29 April 2022, 13:34 SAST · Updated 2 May 2022, 12:37 SAST

## Content

A winter wave of Covid-19 had been [predicted](https://www.power987.co.za/featured/covid-19-fifth-wave-to-hit-sa-during-the-winter-months/) for May in South Africa and experts say they believe Omicron sub-variants are responsible for the current spike in cases.

Coronavirus infections continue to increase, with Gauteng still accounting for most of the new infections in the country, followed by KwaZulu-Natal.

Now, the race is on for them to understand how BA.4 and BA.5 are evading immunity due to prior infection and vaccination.

In case you missed it, we've rounded up our week's coverage of the latest Covid-19 news, Omicron sub-variants and how health regulations might change for you [**here**](https://www.dailymaverick.co.za/section/covid-19/).

Here are some of the highlights:

\[embed\]https://www.dailymaverick.co.za/article/2022-04-28-south-africas-covid-19-positivity-rate-slightly-down-but-still-thousands-of-new-cases/\[/embed\]

\[embed\]https://www.dailymaverick.co.za/article/2022-04-26-race-on-to-study-new-mutations-as-omicron-ba-4-and-ba-5-likely-cause-of-5000-new-sa-covid-cases-overnight/\[/embed\]

\[embed\]https://www.dailymaverick.co.za/article/2022-04-26-high-court-will-rule-next-week-if-sas-covid-19-health-regulations-can-stand/\[/embed\]

*[Subscribe](https://www.dailymaverick.co.za/about/newsletter/) to our Covid-19 newsletter to make sure you don't miss any of the latest information.*