Countries across Europe have been reporting rises in coronavirus infections, prompting debate over whether to reintroduce restrictions and how to persuade more people to get vaccinated.
The daily number of cases was likely inflated by a public holiday in parts of Germany on Monday that led to a delay in data-gathering. The previous record was on Dec. 18, with 33,777 cases.
Helge Braun, chief of staff to acting Chancellor Angela Merkel, said that German states needed to make faster progress in giving older people booster shots.
"That should have happened long ago," he told broadcaster ZDF on Thursday.
As of Wednesday, only 6.7% of people over 60 in Germany had received a booster shot, according to data from the Robert Koch Institute for infectious diseases.
Older people were also more likely to be hospitalised with COVID-19. The number of infected people in hospital stood at 3.62 per 100,000 on Wednesday - up from 1.65 in early October - but at 8.27 per 100,000 for those over 60. (Reporting by Maria Sheahan; Editing by Nick Macfie)
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epa09561335 Robert Koch Institute head Lothar Wieler arrives at a press conference together with German Health Minister Jens Spahn about expanding access in Germany for Covid-19 vaccine booster shots, in Berlin, Germany, 03 November 2021. Spahn has urged states to reopen their mass vaccination centers in order to facilitate the administration of booster shots nationwide. He has said that while priority should be given to the elderly, access should essentially be available to everyone. EPA-EFE/CARSTEN KOALL / POOL